Targeted Therapy Treatment

Targeted therapy is a sophisticated type of cancer treatment, which is aimed at particular molecular or genetic abnormalities that promote cancer development. In contrast to standard chemotherapy which targets cells of rapid division much more widely, targeted therapy is designed to disrupt cellular biological processes with specificity to cancerous cells, allowing that effect to be more limited on normal cells.

Targeted therapy at the Indian Cancer Treatment Centre is provided once the diagnostic and molecular tests have been thoroughly done. Decision made regarding treatment is custom  made, evidence based and in accordance to the international clinical guidelines to make proper and responsible decisions.

What Is Targeted Therapy?

The development of cancer is usually promoted by certain genetic mutations or abnormal proteins which enable the tumor cells to reproduce, live and proliferate. Targeted therapy is based on inhibition of:

• Proteins involved in cancer cell growth

• Genetic mutations within tumor cells

• Signaling pathways that promote tumor survival and progression

Prescription of these medicines is done only after testing of the presence of a relevant biological target. Due to this fact, proper diagnosis and molecular profiling is necessary before beginning therapy.

Cancers Commonly Treated with Targeted Therapy

Targeted therapy is useful in the treatment of various cancers such as:

• Breast cancer

• Lung cancer

• Colorectal cancer

• Head and neck cancers

• Gastrointestinal stromal tumors (GIST)

• Certain leukemias and lymphomas

Targeted Therapy Approach at ICTC

Precision Diagnostics

Prior to the commencement of targeted therapy, the patient is thoroughly assessed which might involve:

• Histopathological confirmation of diagnosis

• Molecular and genetic testing when clinically indicated

• Biomarker analysis to identify actionable targets

This systematic diagnostics process has been chosen so that therapy is chosen in accordance with scientific evidence and tumor biology.

Individualized Treatment Planning

Every treatment plan is formulated with respect to:

• Tumor biology and molecular profile

• Evidence based international guidelines

• Patient’s overall health status and previous treatments

The aim is to ensure maximization of the therapeutic benefit without compromising the safety.

Multidisciplinary Care

Multidisciplinary approach to treatment involves coordinating treatment decisions which involve:

• Medical oncologists

• Pathologists

• Molecular diagnostics specialists

• Radiology and supportive care teams

This is an interprofessional model that promotes holistic and combined cancer care.

How Targeted Therapy Is Given

Depending on the type of medication and type of cancer, targeted therapy can be given in various forms:

• Oral medications such as tablets or capsules

• Intravenous infusions

Treatment schedules vary according to the specific drug protocol. Patients are monitored regularly to assess treatment response and manage any side effects.

Side Effects and Monitoring

The side effects profile of targeted therapy is usually dissimilar to chemotherapy. Although it is more likely to be tolerated, it may lead to such effects as:

• Skin and nail changes

• Fatigue

• Blood pressure variations

• Gastrointestinal symptoms

Follow up check up appointments and lab check ups should be done regularly to ensure safe treatment continuity. When needed, the dose adjustments or supportive interventions are given.

Why Choose ICTC for Targeted Therapy?

• Access to precision oncology diagnostics

• Evidence based selection of targeted agents

• Experienced oncology specialists

• Integrated chemotherapy, immunotherapy, and supportive care services

• Ethical and transparent treatment planning

At ICTC, targeted therapy is guided by careful testing and multidisciplinary expertise, ensuring that advanced treatments are used appropriately and responsibly.